Andrée-Ann Baril, Ph.D.
Assistant Research Professor
Department of Medicine, Université de Montréal
andree-ann.baril@umontreal.ca
Training
Posdoctoral fellowship in Psychiatry (McGill University)
Posdoctoral fellowship in Neurology and Epidemiology (Boston University)
Ph.D. in Biomedical Sciences (Université de Montréal)
Research interests
Investiguate the association between insomnia and sleep disturbances in relation with Alzheimer's disease risk, and underlying mechanisms
Methodological approaches
Polysomnography, actigraphy, 'omics' research (proteomics, genomics), neuroimaging, neuropsychology, cognitive behavioral therapy for insomnia
Fundings
New Investigator Grant, Operating Grant
Alzheimer Society of Canada
Canadian Institutes of Health Research – Aging institute
Role: Principal investigator
Title: Plasma biomarkers of Alzheimer’s disease in insomnia before and after cognitive behavioral therapy for insomnia
Years: 2023-2026
Chercheur-boursier Junior 1
Fonds de recherche du Québec en santé (FRQS)
Role: Principal investigator
Years: 2024-2028
Bilateral collaborative research program FRQS-Inserm, cognitive aging
Fonds de recherche du Québec en santé (FRQS)
Role: Principal investigator
Years: 2024-2027
Career Development Award
Sleep Research Society Foundation
Role: Principal investigator
Years: 2024-2025
My team
Marie-Josée Quinn, T.M.
Coordo-Medical laboratory technician, responsible for the Biobank
Tyna Paquette, Ph.D.
Research Associate
Julien Beaudry, B. Ing, M.Sc.
Software Developer
Julie Otis, T.M.
Medical Laboratory Technician
Caroline d’Aragon, B.Sc., T.I.M.
Research coordinator
Rayan Daoudi
Research Assistant
Beatriz Mendoca de Oliveira, M.Sc.
Ph.D. candidate
Bery Mohammediyan, M.Sc.
Candidate au PhD
Vincent Rivest
Research Assistant
Selected publications
BARIL AA, Picard C, Labonté A, Sanchez E, Duclos C, Mohammediyan B, Breitner JCS, Villeneuve S, Poirier J, PREVENT-AD Research Group. Longer sleep duration and neuroinflammation in at-risk elderly with a parental history of Alzheimer’s disease. SLEEP, 2024, zsae081.
BARIL AA, Picard C, Labonté A, Sanchez E, Duclos C, Mohammediyan B, Ashton NJ, Zetterberg H, Blennow K, Breitner JCS, Villeneuve S, Poirier J, PREVENT-AD Research Group. Day-to-day variability with Alzheimer’s disease biomarkers in at-risk elderly. Alzheimer’s & Dementia: Diagnosis Assessment & Disease Monitoring, 2024,16(1), e12521.
Yiallourou S1, Cribb L1, Cavuoto M, Rowsthorn E, Nicolazzo J, Gibson M, BARIL AA2, Pase M2 (1Joint first authors, 2Joint senior authors). Association of the sleep regularity index with incident dementia and brain volume. Neurology, 2024, 102(2), e208029.
Cribb L1, Sha R1, Yiallourou S1, Grima NA, Cavuoto M, BARIL AA2, Pase M2 (1Joint first authors, 2Joint last authors). Sleep regularity and mortality: A prospective analysis in the UK Biobank. eLife, 2023, 12, RP88359.
Himali J, BARIL AA, Cavuoto MG, Yiallourou S, Wiedner CD, Himali D, DeCarli C, Redline S, Beiser AS, Seshadri S, Pase MP. Association between slow-wave sleep loss and incident dementia. JAMA Neurology, 2023, e233889.
Baril AA, Beiser A, Sanchez E, Mysliwiec V, Redline S, Gottlieb DJ, O’Connor GT, Gonzales MM, Himali D, Seshadri S, Himali J*, Pase M* (*These authors contributed equally). Insomnia symptom severity and cognitive performance: moderating role of APOE genotype. Alzheimer’s & Dementia, 2022, 18(3), 408-21.
Baril AA, Beiser AS, Mysliwiec V, Sanchez E, DeCarli CS, Redline S, Gottlieb DJ, Maillard P, Romero JR, Satizabal CL, Zucker JM, Seshadri S, Pase MP*, Himali JJ* (*These authors contributed equally). Slow-wave sleep and MRI markers of aging in a community-based sample. Neurology, 2021, 96(10), e1462-1469.
Baril AA, Beiser AS, Redline S, McGrath ER, Aparicio JH, Gottlieb DJ, Seshadri S, Pase MP*, Himali JJ* (*These authors contributed equally). Systemic inflammation as a moderator between sleep and incident dementia. SLEEP, 2021, 44(2), zsaa164.
Projects
Epidemiological link between sleep disturbances and Alzheimer's disease risk and cognitive, neuroimaging, proteomics, and genomics biomarkers in large cohorts.
Plasma biomarkers of Alzheimer's disease and inflammation in diagnosed insomnia before and after cognitive behavioral therapy for insomnia.
Optimal sleep characteristic determinants of the regulation of physiological functions with proteomic blood-based signatures.